Liver cancer is a type of cancer that is most commonly found in males. The prevalence of the disease in males is attributed to the role that alcohol plays in the progression of the cancer. Of course there are other causes of liver cancer but mostly alcohol abuse speeds up the disease process.
Liver cancer can also be treated surgically to eliminate the affected part of the liver with cancerous cells. Surgical options are usually reserved for the small-sized cancers of the liver. Complications from surgical removal might include bleeding (usually severe), bacterial infection, and scarring (extensive). Other risk factors that have been associated with liver cancer risk factors are age (elderly people tend to have higher risk), color of skin (darkly pigmented people have increased risk), and family history (an unexpected sibling would increase risk).
There are several types of primary liver cancers. The two most common types are hepatocellular carcinoma and adenocarcinoma. Hepatocellular carcinoma accounts for approximately 90 percent of all primary liver cancers. Primary hepatic adenocarcinomas are also quite common. Both adenocarcinomas and hepatocellular carcinomas can spread to the other organs if they are not removed during the surgery.
There are several factors that can increase the risk of developing these types of liver cancer. They include: benign tumors – these tumors are usually not malignant (cancerous) and will not spread to other parts of the body; malignant tumors – these tumors are malignant and will spread to other parts of your body if left untreated; obesity; age (as people get older, they become more likely to develop cancer of any kind) and male sex (women have a greater risk of developing carcinoma in comparison to men). Cancer of the hepatica, which is a type of cancer that affects the liver, is one of the few types of cancer that does not occur only in older people. Approximately one in fifty adults will contract hepatocellular carcinoma. Other forms of cancer of the liver include melanoma, myeloid leukemia, renal cell carcinoma, bladder cancer, multiple myeloma, lymphoma, pauciacral mesothelioma and squamous cell carcinoma.
The risk factors associated with liver cancer in Asian Americans or patients who are members of the Asian American population are often more severe than those found in patients of other ethnicities or with doctors reporting the same symptoms. In other words, when it comes to risk factors, Asians are worse off than others. There are several risk factors that apply particularly to patients of Asian heritage: their gender (women are more likely to contract hepatocellular carcinoma than men); their age (the median age of patients is increasing as the number of ethnic groups increases, especially for Asian Americans); their ethnicity (congrats, east Asians and south Asians are more likely to suffer from this disease than whites); their culture (Asians have a very diverse diet); and their health (they live longer on average than whites and are less likely to engage in unhealthy behaviors). One of the strongest risk factors for liver cancer is a history of hepatitis B or C, which can result from either an ancestral history of these infections or exposure to hepatitis B or C virus during childhood.
Another strong risk factor is a history of alcohol abuse, which can increase a person’s risk of developing liver cancer. In addition, certain ethnic groups are at higher risk than others, especially for women. Hispanics, African Americans, Asians and American Indians all have a higher rate of alcohol abuse and liver cirrhosis than white Americans. Another risk factor for both men and women is the presence of Hepatitis C Virus (HCV) in the blood, which remains inactive in the blood and is only activated if a person has been exposed to hepatitis B or C virus. Thus, those patients who had been exposed to HCV and have not yet developed cirrhosis are at a lower risk of developing liver cancer.
Some patients have a genetic disposition towards this condition and have increased risk of developing liver cancer. Genes that code for amino acid homocysteine (AAHD) also play an important role in determining the risk of cirrhosis. In patients with cirrhosis, excess hemoglobin (a blood component composed mainly of red blood cells) in the liver cells is converted into AHD, which is involved in the development of liver inflammation and cell damage. Increased AHD levels can occur due to genetic changes in the liver. Some studies have shown that patients suffering from chronic alcoholic hepatitis (chronic excessive alcohol consumption, or ACOH) have greater amounts of AHD in their liver cells than do people who do not suffer from chronic alcohol consumption. Patients with genetical disorders of the liver such as hemochromatosis, Wilson’s disease and congenital heart disease are at greater risk of developing cirrhosis.
Other factors that affect a person’s risk of developing cirrhosis are being male, old, female, diabetic, and hypertensive. Men are twice as likely as women to develop cirrhosis. Alcohol abuse can increase the risk of developing cirrhosis. People who consume alcohol in excess over a period of time or those who drink alcohol regularly have a greater risk of developing cirrhosis of the liver. It has also been shown that alcohol abuse increases the risk of developing different types of cancer of the liver in both men and women. People who abuse alcohol are more likely to have higher levels of triglycerides (fatty components in the bloodstream), higher levels of high-density lipoprotein (HDL) and lower levels of high-density cholesterol (LDL).
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